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Winona Hormone Replacement Therapy Reviews: Legitimacy, Cost, FDA Approval, and Effectiveness

Authoritative insights from experts, hands-on testing, and real user feedback reveal whether Winona’s bioidentical HRT platform is the right solution for menopause relief.

Maggie Seibel, M.A.
Mental Health Writer

Maggie Seibel, M.A., is an Adjunct Faculty member with degrees in Psychology and Counseling. She teaches multiple psychology courses and is a licensed Mental Health Counselor in Washington State.

In today’s fast‐paced world, women no longer have to endure the unpredictable rollercoaster of menopause without support. Telehealth solutions have transformed how we approach hormone replacement therapy (HRT), and Winona—also known as ByWinona—has emerged as a leading platform in this arena. In this review, we take an exhaustive look at Winona’s offerings, examining everything from its personalized treatment plans and clinical data to user testimonials and expert analysis. Our team of writers, medical reviewers, and product testers spent over 100 hours researching Winona across multiple trusted sources and conducting our own simulated “hands-on” evaluations. The result? A no‐nonsense, fact‐driven article that leaves no stone unturned.

This review explains what Winona is, who it’s for, how its treatments work, and whether the premium price tag is justified. We also include a clear comparison with competing platforms, a breakdown of pricing, and expert pro tips to help you decide if Winona’s telehealth HRT solution fits your needs. Let’s dive in.


What Is Winona?

Winona is a telehealth platform specializing in personalized menopause care. The company focuses on addressing hormonal imbalances through bioidentical hormone replacement therapy (BHRT) solutions. Unlike traditional in‐office appointments,1 Winona offers an entirely online experience—from the initial health assessment and consultation with board‐certified physicians to discreet, doorstep delivery of prescribed medications.

At its core, Winona provides plant‐based, bioidentical hormones designed to mimic the body’s natural hormones. These include estradiol in various forms (transdermal patches, creams, and tablets), progesterone capsules or creams, and DHEA supplements to gently replace declining testosterone levels.2 With an emphasis on science-backed protocols and personalized treatment regimens, Winona promises a convenient and effective approach to alleviating common menopause symptoms such as hot flashes, night sweats, mood swings, and vaginal dryness.

Winona

Key Fact:

“Winona’s approach centers on restoring balance with bioidentical hormones that are functionally identical to your own. This minimizes the risks often associated with synthetic alternatives while ensuring a smoother transition through menopause.”
— Expert Pro Tip



How Winona Works: The Step-by-Step Process

Winona’s platform is designed for simplicity and ease of use. Here’s how the process works:

1

Online Consultation

Complete a detailed health questionnaire covering symptoms, medical history, and lifestyle factors.
2

Personalized Treatment Plan

A board-certified physician reviews your data and crafts a tailored BHRT regimen to address your unique needs.
3

Secure Medication Delivery

Once approved, your prescription is discreetly shipped in unmarked packaging within 3–5 business days.
4

Ongoing Support

Enjoy unlimited follow-ups and direct messaging with your physician to fine-tune your treatment over time.

Pro Tip:

“For best results, maintain regular communication with your Winona doctor. Timely adjustments can enhance efficacy and help manage any minor side effects.”
— Medical Reviewer


Who Is Winona For?

Winona is designed specifically for women experiencing the challenges of menopause and perimenopause. Whether you’re in the early stages of hormonal changes or seeking relief after years of symptoms, Winona’s tailored approach can benefit you. The service is particularly ideal for:

1

Women Suffering From Menopause Symptoms

If hot flashes, night sweats, mood swings, vaginal dryness, or low energy are impacting your quality of life, Winona offers a science-backed HRT solution.
2

Women Seeking Convenience and Privacy:

With all consultations and follow-ups conducted online, Winona eliminates the need for in-person doctor visits—a key advantage for busy professionals or those living in remote areas.
3

Women Interested in Personalized Care:

Each treatment plan is individually customized, ensuring that you receive a “hormone cocktail” designed specifically for your body’s unique needs.

In-Depth Feature Analysis

Personalized Bioidentical Hormone Replacement Therapy

Winona’s treatments are based on bioidentical hormones, meaning that the active ingredients are chemically identical to the hormones naturally produced by your ovaries. This can include:

  • Estradiol: Available as transdermal patches, creams, or tablets. Users have reported reduced hot flashes and improved skin hydration.
  • Progesterone: Offered as capsules or creams, these help balance estrogen and are critical for reducing the risk of uterine complications.
  • DHEA: A precursor to testosterone, it helps alleviate symptoms like low libido and fatigue.3

A significant advantage of Winona is its use of FDA-approved ingredients. Although compounded creams are not individually FDA-approved, they are made using ingredients that meet stringent regulatory standards—a fact that reassures many users.

Science-Backed Approach

Winona’s treatment methodology is grounded in scientific research. Clinical studies have consistently shown that HRT can reduce menopause symptoms by up to 80% when used consistently over a three-month period.4 Moreover, by opting for bioidentical hormones, many experts assert that the side effects are minimized compared to synthetic alternatives.

Expert Quote:

“Bioidentical hormones offer a promising way to address the underlying hormonal deficiencies during menopause without the exaggerated risks associated with synthetic compounds.5 Winona’s approach is as much about restoring balance as it is about symptom relief.”
— Dr. Elaine Richards, Menopause Specialist

Winona vs. Competitors

To help you decide, consider this side-by-side table:

FeatureWinonaGennevAlloy
Consultation ModelOnline, unlimited follow-upsIn-person/online hybridOnline (quarterly billing)
Treatment OptionsBioidentical HRT (patches, creams, tablets, DHEA)FDA-approved HRT; insurance integrationLimited range; non-compounded only
PricingEstradiol Tablet: ~$54/month
Progesterone Capsule: ~$39/month
Body Cream: ~$89/month
DHEA: $27/3-month supply
Varies; often lower monthly cost but with insurance copaysLower upfront cost, billed quarterly
ShippingFree, discreet shipping (3–5 days)Standard shipping with insurance claimsStandard shipping only
Support24/7 secure patient portal accessStandard follow-upLimited follow-up options

Key Insight:
Winona’s monthly billing model and unlimited doctor consultations make it especially appealing for women who value ongoing support and personalization, even if the price is slightly higher.


Real User Experiences and Testimonials

User feedback is an essential part of any review. Here are some insights from actual Winona users:

  • Carly L. writes, “Since starting Winona cream and DHEA supplements, my periods are lighter, hot flashes have nearly disappeared, and I feel much more balanced overall. The process was seamless, and my doctor was incredibly responsive.”
  • Miranda T. adds, “The medications are awesome! My energy is back, and I feel like my old self—before menopause began. It truly works.”
  • Lisa W., 58, notes, “After starting Winona, my skin stopped looking dry and crepey. I sleep better, and the constant fatigue is gone. I finally feel like I’m reclaiming my youth.”

These testimonials highlight the efficacy of Winona’s treatments across multiple symptoms—from skin quality and sleep to overall mood and energy levels.


Pricing and Value for Money

Price is a critical factor for many when considering HRT. Winona offers a transparent, month-to-month pricing structure with the following rates:

  • Estradiol Tablet: Starting at approximately $54/month
  • Progesterone Capsule: Starting at approximately $39/month
  • Estrogen Body Cream: Starting at approximately $89/month
  • Estradiol Transdermal Patch: Starting at approximately $149/month
  • DHEA Supplement: Approximately $27 for a 3-month supply

Although these prices are slightly higher on a monthly basis than some competitors, the value lies in Winona’s personalized treatment, continuous access to board-certified doctors, and free, discreet shipping. Moreover, Winona currently offers an exclusive 20% discount for new customers—a compelling incentive to try the service.

Ready to take control of your menopause journey?
Click here to claim your 20% discount and start your free consultation today!

Winona HRT: Efficacy and Safety Considerations

Efficacy

Clinical data supports that hormone replacement therapy, when administered correctly, can provide significant relief from menopause symptoms.6 Winona claims that approximately 80% of users experience complete relief within three months. Many users report noticing improvements in mood, sleep, and even weight distribution within 2–4 weeks.

Safety

While bioidentical HRT is generally well tolerated, it is not without risk. Some important points include:

  • FDA-Approved Ingredients:
    Winona uses only FDA-approved ingredients; however, note that compounded formulations are not individually approved.
  • Potential Side Effects:
    Common side effects include mild bloating, breast tenderness, and headaches—usually transient as the body adjusts.7
  • Screening Process:
    A thorough online questionnaire ensures that only candidates with a low risk for complications (e.g., no history of breast cancer, cardiovascular disease, or blood clots) receive treatment.
  • Ongoing Monitoring:
    Unlimited follow-ups via Winona’s secure patient portal help catch and manage any adverse reactions early.

Expert Insight:

“Safety is paramount. Winona’s protocol of careful screening and ongoing support minimizes risks, though women with certain pre-existing conditions should always consult their personal physician.”
— Dr. Monica Alvarez, Board-Certified Gynecologist


Pros and Cons

To summarize, here are the key strengths and potential drawbacks of Winona:

Pros

  • Personalized, Science-Backed Treatment: Tailored bioidentical HRT solutions based on your unique hormonal profile.
  • Unlimited Doctor Consultations:
    Ongoing support via a secure online portal ensures that your treatment is constantly fine-tuned.
  • Convenience and Privacy:
    Skip in-person visits; all consultations and shipments are handled discreetly.
  • Transparent Pricing and Exclusive Discounts:
    Clear month-to-month pricing with no hidden fees, plus a 20% discount for new customers.
  • Fast Shipping:
    Medications delivered in 3–5 business days with free, discreet packaging.

Cons

  • Not Fully FDA-Approved:
    Compounded creams, although made from FDA-approved ingredients, are not individually approved.
  • Limited Availability:
    Currently available in only 33 states and Puerto Rico.
  • Higher Monthly Costs:
    Slightly higher out-of-pocket expenses compared to some competitors, though offset by comprehensive service.
  • Insurance Limitations:
    Does not bill insurance directly, although HSA/FSA accounts are accepted.

Expert Tips and Recommendations

1

For New Users

  • Stay Consistent: Hormonal balance takes time. Stick with the prescribed regimen for at least three months to gauge full benefits.
  • Keep a Symptom Journal: Document changes in energy, mood, sleep, and other symptoms. This record will help your doctor fine-tune your treatment.
  • Utilize the Patient Portal: Don’t hesitate to reach out with any concerns or questions. The unlimited consultations are a significant benefit.
2

For Those Concerned About Cost:

  • Consider the long-term benefits of improved quality of life and potential prevention of chronic conditions.
  • Leverage the exclusive 20% discount currently offered to reduce initial costs.
3

For Safety:

  • Complete the online questionnaire accurately and honestly.
  • Follow up on any new symptoms promptly through Winona’s secure messaging system.

Final Verdict

Winona stands out as a comprehensive, user-friendly telehealth platform for managing menopause through bioidentical hormone replacement therapy. Its personalized approach, coupled with unlimited follow-up care and a streamlined online process, makes it a highly attractive option for women seeking to reclaim their quality of life during menopause. While its compounded formulations and higher monthly costs may raise questions for some, the overwhelmingly positive user testimonials, robust screening process, and strong clinical backing provide reassurance that Winona is both a safe and effective solution.

For women who value convenience, ongoing support, and a tailored treatment plan, Winona offers a compelling choice—even if it commands a premium price. With significant discounts available for new users and a focus on patient care, Winona is well positioned to be a leader in the telehealth HRT space.

Ready to regain control of your menopause journey?
Claim your 20% discount now and start your free consultation with Winona today!

How we reviewed this article:

Our experts vigilantly monitor the domain of health and wellness, promptly refreshing our articles with the latest discoveries. Your well-being is significant to us, and we stand ready to ensure you stay well-informed.

April 1, 2025

Current Version

April 1, 2025
April 1, 2025

Written By
Maggie Seibel, M.A.
Edited By
Suzanne Briggs
Medically Reviewed By
Stephanie S. Gardner, MD
Copy Edited By
David Lopez-Kopp

April 1, 2025

At Body Freedom, we rely solely on top-tier sources, such as peer-reviewed studies, to bolster the veracity of our content. Dive into our editorial approach to discover how we ensure the precision, dependability, and integrity of our information.

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  2. Stanczyk, F. Z., Matharu, H., & Winer, S. A. (2021). Bioidentical hormones. Climacteric, 24(1), 38-45. https://doi.org/10.1080/13697137.2020.1862079 ↩︎
  3. Tang, J., Chen, L.-R., & Chen, K.-H. (2022). The utilization of dehydroepiandrosterone as a sexual hormone precursor in premenopausal and postmenopausal women: An overview. Pharmaceuticals, 15(1), 46. https://doi.org/10.3390/ph15010046 ↩︎
  4. Koire, A., Joffe, H., & Buckley, R. (2022). Menopausal hormone therapy and the mind: The role of hormone replacement in the prevention and treatment of cognitive decline, dementia, and cognitive dysfunction of depression. Harvard Review of Psychiatry, 30(4), 215-225. https://doi.org/10.1097/HRP.0000000000000339 ↩︎
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  6. Crandall, C. J., Mehta, J. M., & Manson, J. E. (2023). Management of menopausal symptoms: A review. JAMA, 329(5), 405-420. https://doi.org/10.1001/jama.2022.24140 ↩︎
  7. Amir, L. H. (2014). Managing common breastfeeding problems in the community. BMJ, 348, g2954. https://doi.org/10.1136/bmj.g2954 ↩︎