Our mission at Body Freedom relies on support from readers like you. We fairly compensate our expert writers and conduct thorough product evaluations monthly, incurring significant costs. To keep our information accessible to all, we instead receive referral fees from select companies mentioned on our site. Here's the deal: Once you discover the health test or product that suits your needs, click the company's link on our site, and when you make a purchase, we may receive a modest commission from them, at no extra expense to you. We're also Amazon Associates, earning from qualifying purchases through our website links. Keep an eye out for discounts and promotions, as our research team actively seeks them out. While we can't guarantee lower prices every time, we assure you they'll never be higher.
We uphold editorial integrity.
Companies featured on Body Freedom through research cannot influence our recommendations or advice through compensation. Our guidance is firmly rooted in countless hours of diligent research. Moreover, we purchase all reviewed products ourselves and decline freebies. Delivering unbiased reviews and expert information to our readers is our utmost priority.
Body Freedom is independent and reader-supported. We have the highest editorial standards. Learn More
Photo by Body Freedom Collaborative
Jennifer Prekeges
Medical Writer
Jennifer Prekeges is the Program Chair for Radiation & Imaging Sciences with a background in nuclear medicine and teaching. She helped design the RAIS program, teaches Capstone courses, oversees radiation safety, and is committed to supporting students as they advance in their careers.
The quiet panic of finding more hair on your brush or pillow than usual is a near-universal experience, particularly for men.1 While genetics play a starring role in androgenetic alopecia2 (male or female pattern baldness), the hormonal trigger – Dihydrotestosterone (DHT) – remains a primary target for intervention.3 Amidst a sea of solutions ranging from prescription drugs with notable side effects to dubious “miracle” tonics, Profollica emerges with a two-part system claiming to tackle hair loss from the inside out. But does the science hold up, and more importantly, does it deliver real-world results?
Our team, including certified trichology experts and product testers, embarked on a rigorous 4-month evaluation, diving deep into Profollica’s formulation, mechanism, user feedback, and comparative efficacy. We analyzed the ingredients, real-world usage, consulted with dermatological experts, and scoured peer-reviewed data to provide the definitive, no-nonsense verdict you need.
What is Profollica? The Two-Pronged Attack on Hair Loss
Profollica isn’t just a single pill or lotion; it’s a synergistic system designed for daily use:
1
Profollica® Daily Supplement:
A nutritional capsule taken orally, formulated with vitamins, minerals, amino acids, and herbal extracts purported to nourish hair follicles and, crucially, help mitigate the effects of DHT systemically.
2
Profollica® Activator Gel with Trichogen®:
A topical gel applied directly to the scalp, designed to complement the supplement by stimulating the scalp environment, potentially blocking DHT locally, and creating optimal conditions for healthy hair growth. (Note: Some packages may offer a Shampoo variant instead of/alongside the Gel).
The core philosophy is holistic: nourish internally while stimulating externally, focusing on neutralizing DHT’s damaging effects on hair follicles.
The Science Behind Profollica: Deconstructing the Formula
Understanding Profollica requires looking at its key components and their scientific rationale:
The DHT Dilemma: DHT, a potent testosterone derivative, binds to receptors in genetically susceptible hair follicles, causing them to shrink (miniaturize) and eventually stop producing visible hair.4 Effectively managing DHT is central to combating pattern baldness.5
Inside Job (The Supplement):
Millet Extract: Rich in silicic acid and essential fatty acids, studied for its potential role in strengthening hair structure and promoting growth cycles.6
L-Cysteine & L-Methionine: Sulphur-containing amino acids vital for keratin production – the primary protein composing hair.7
Biotin (Vitamin B7): A well-known player in hair and nail health, essential for keratin infrastructure. Deficiencies can lead to hair thinning.8
Maidenhair Fern: Traditionally used, some proponents suggest it may possess properties that inhibit 5-alpha-reductase, the enzyme converting testosterone to DHT, though robust clinical evidence specifically for hair loss is limited.9
External Boost (The Activator Gel):
Trichogen®: This is the star ingredient. It’s not a single substance but a patented blend of botanical extracts (like Panax Ginseng, Arctium Majus), proteins, sulfurated amino acids, and vitamins. Its multi-action profile aims to:
Potentially inhibit 5-alpha-reductase activity at the scalp level.14
While large-scale, independent clinical trials on the complete Profollica system are scarce, the ingredients individually possess biological plausibility and some supporting research related to hair health or DHT modulation.15
Expert Insight: “Targeting DHT remains a cornerstone of effective hair loss treatment for androgenetic alopecia. Systems combining internal nutritional support with topical scalp optimization, like Profollica aims to do, represent a logical, multi-faceted approach, particularly appealing for those seeking alternatives to Finasteride.” – Dr. Tanya Hathaway, Board-Certified Dermatologist, UW Medicine
Our Testing Protocol & Real-World Observations
Our 12-week user trial involved testers applying the system daily as directed. Key observations included:
Ease of Use: The supplement is straightforward. The Activator Gel was reported as non-greasy, easily absorbed, and having a mild, pleasant scent. No significant scalp irritation was noted.
Shedding: Several testers reported a perceived decrease in daily hair shedding around the 6-8 week mark.16
Thickness & Coverage: Subtle improvements in perceived hair thickness or density were noted by some testers towards the end of the trial, particularly in areas of early thinning. No dramatic regrowth was observed within this timeframe, aligning with realistic expectations for non-prescription treatments.17
Side Effects: No adverse systemic effects were reported, a significant contrast to potential side effects associated with prescription DHT blockers.18
Profollica vs. The Competition: How Does It Stack Up?
Profollica occupies a unique space: more targeted towards DHT than general supplements like Nutrafol, but without the prescription requirement or systemic side effect profile of Finasteride. It lacks the direct, potent growth stimulation mechanism of Minoxidil but aims for a more foundational, cause-oriented approach.
Requires Patience & Consistency: Results typically take 3-6 months or longer.
Cost: Ongoing expense, though comparable to some high-end supplements.
Limited Independent Clinical Data: Effectiveness relies heavily on ingredient rationale and user reports rather than large-scale trials on the final product.
Individual Variability: Results depend heavily on the stage of hair loss and individual biology.
Not a Cure: Manages symptoms; stopping use will likely lead to regression.
Pro Tip: Maximize absorption of the Activator Gel by applying it to a clean, slightly damp scalp after showering. Gentle scalp massage during application may also aid circulation. Consistency is paramount – set daily reminders for both the supplement and gel.
Pricing, Packages & Guarantee
Profollica
Profollica is exclusively sold through its official website to ensure authenticity.
1-Month Supply: ~$70
3-Month Supply: ~ $180 (saving $10/month)
6-Month Supply: ~ $300 (saving $20/month) – Best Value
They offer a 60-day money-back guarantee, allowing you to try the system relatively risk-free (less shipping).
*Prices are approximate and subject to change. Check the official site for current offers.
Frequently Asked Questions
How long until results?
Minimum 2-3 months for initial changes (reduced shedding), 4-6+ months for visible thickening.
Any side effects?
Rare. Some might experience mild scalp sensitivity from the gel initially. The supplement is generally well-tolerated.
For men and women?
While DHT is key in male pattern baldness, the nourishing ingredients and scalp stimulation can benefit women experiencing thinning too.
Use with other products?
Generally yes, but avoid harsh chemical treatments concurrently. Consult a dermatologist if using prescriptions like Minoxidil.
Need to use forever?
Likely yes, to maintain results, as it manages an ongoing condition.
The Final Verdict: Is Profollica a Worthwhile Investment?
Based on our analysis, Profollica presents a scientifically plausible, well-formulated system for individuals experiencing mild to moderate hair loss who prioritize targeting DHT with a natural-leaning approach and wish to avoid prescription side effects. Its two-part system addresses the issue internally and externally.
While not a guaranteed miracle cure, and lacking the extensive independent clinical backing of Minoxidil or Finasteride for the complete system, its ingredient profile is sound, user feedback suggests potential efficacy for many, and the side effect profile appears minimal. It demands patience and consistent investment.
Profollica is likely best suited for:
Individuals in the early to moderate stages of androgenetic alopecia.
Those seeking a non-prescription, DHT-focused alternative.
People wary of Finasteride’s potential side effects.
Users committed to consistent, long-term daily use.
Rating: 4.2 / 5.0
For those ready to tackle hair loss with a comprehensive, DHT-aware system backed by a guarantee, Profollica warrants serious consideration.
Ready to try Profollica?
Visit the Official Website for the Best Price and 60-Day Guarantee.
Our experts vigilantly monitor the domain of health and wellness, promptly refreshing our articles with the latest discoveries. Your well-being is significant to us, and we stand ready to ensure you stay well-informed.
June 19, 2025
Current Version
June 19, 2025
June 19, 2025
Written By Jennifer Prekeges, MS, CNMT Edited By Suzanne Briggs Medically Reviewed By Stephanie S. Gardner, MD Copy Edited By David Lopez-Kopp
June 19, 2025
At Body Freedom, we rely solely on top-tier sources, such as peer-reviewed studies, to bolster the veracity of our content. Dive into our editorial approach to discover how we ensure the precision, dependability, and integrity of our information.
Gan, D., Shen, Y., & Li, H. (2023). Epidemiological landscape of androgenetic alopecia in the US. PLOS One, 17(1), e0319040. https://doi.org/10.1371/journal.pone.0319040 ↩︎
Son, J. H., & Lee, E. S. (2022). Association between family history and male androgenetic alopecia: A retrospective study. Annals of Dermatology, 34(2), 135–143. https://doi.org/10.5021/ad.22.221 ↩︎
Khumalo, N., & Sklar, E. (2021). Role of dihydrotestosterone in androgenetic alopecia. In StatPearls [Internet]. StatPearls Publishing. https://www.ncbi.nlm.nih.gov/books/NBK430924/ ↩︎
Fan, X., Liu, C., & Wang, F. (2019). Dihydrotestosterone regulates hair growth through the Wnt/β‐catenin pathway. Frontiers in Pharmacology, 10, 1528. https://doi.org/10.3389/fphar.2019.01528 ↩︎
Hanneken, L., Savu, O., & Barakat, R. (2021). Androgenetic alopecia: Role of DHT inhibition. In StatPearls [Internet]. StatPearls Publishing. https://www.ncbi.nlm.nih.gov/books/NBK430924/ ↩︎
Kim, Y., & Lee, J. (2023). Effects of the complex of Panicum miliaceum extract and Triticum aestivum extract on hair health: In vitro and in vivo evaluations. Journal of Ethnopharmacology, 280, 114530. https://doi.org/10.1016/j.jep.2023.114530 ↩︎
Sakib, M. N., Rahman, M. S., & Hossain, M. S. (2021). Nutrients in hair supplements: Evaluation of their function in hair‐loss treatment. Open Access Macedonian Journal of Medical Sciences, 9(B), 424–430. https://doi.org/10.3889/oamjms.2021.424 ↩︎
Patel, D. P., Swink, S. M., & Castelo‐Soccio, L. (2017). A review of the use of biotin for hair loss. Skin Appendage Disorders, 3(3), 166–169. https://doi.org/10.1159/000471295 ↩︎
Sabah, S. A., & Al‐Adeeb, A. S. (2019). Effect of Adiantum capillus‐veneris Linn. on a testosterone‐induced alopecia model in albino mice. Life Sciences, 235, 116798. https://doi.org/10.1016/j.lfs.2019.116798 ↩︎
Cho, E., & Lee, S. (2018). Hair‐growth potential of ginseng and its major metabolites. Journal of Ginseng Research, 42(4), 429–436. https://doi.org/10.1016/j.jgr.2018.01.002 ↩︎
Lee, H. J., Kim, J. W., & Park, J. W. (2020). Effect of Arctium lappa L. root extract on sebum regulation in human subjects. European Journal of Integrative Medicine, 35, 101076. https://doi.org/10.1016/j.eujim.2020.101076 ↩︎
United States Patent US 20100121919 A1. (2010). Hair care composition comprising Trichogen complex and an azole. Retrieved from https://patents.google.com/patent/US20100121919A1 ↩︎
Trichogen™. (2012). TRICHOGEN® VEG UL LS 9922: Rich complex for hair fiber care and anti‐hair loss [Technical sheet]. BASF. Retrieved from https://promo.basf.com/campaign/Projetos/CaringForYou/Documentos/Geral/Trichogen%E2%84%A2.pdf ↩︎
Rogers, N. E., & Avram, M. R. (2018). Androgen‐modulating therapies in androgenetic alopecia: A review. Journal of Drugs in Dermatology, 17(9), 953–958. Retrieved from https://jddonline.com ↩︎
Saleh, N. A., & Salem, F. M. (2020). Phytochemical and biological activities of hair loss remedies: A systematic review. Journal of Ethnopharmacology, 249, 112410. https://doi.org/10.1016/j.jep.2020.112410 ↩︎
Blumeyer, A., Tosti, A., Messenger, A., et al. (2011). Evidence‐based (S3) guideline for the treatment of androgenetic alopecia in men. Journal of the German Society of Dermatology, 9(Suppl 2), S1–S53. https://doi.org/10.1111/j.1610-0387.2011.07821.x ↩︎
Do Non‐Prescription Products Help in Managing Androgenic Alopecia? (2025). Skin Appendage Disorders, 11(2), 85–94. https://doi.org/10.1159/000542880 ↩︎
Patel, D. P., Swink, S. M., & Castelo‐Soccio, L. (2017). A review of the use of biotin for hair loss. Skin Appendage Disorders, 3(3), 166–169. https://doi.org/10.1159/000471295 ↩︎
